Endocrine Abstracts

Introduction: Levothyroxine is the first choice treatment for patients with hypothyroidism However, some people would continue to have symptoms of thyroid disease despite biochemical control on levothyroxine. Others might be intolerant to levothyroxine.Aim: The aim of this audit is to evaluate UHL endocrinology practice against local and national guidelines with regards to prescribing and monitoring of liothyronine treatment in 2019.<p class="abstext...

Introduction: The hypercortisolaemic state of Cushing’s syndrome can lead to ophthalmic complications. We present two case reports of rare association of central serous retinopathy (CSR) and Cushing’s syndrome.Case 1: A 46-year-old man presented with gradual deteriorating vision. He was diagnosed with CSR and was referred to the Endocrine department for screening for Cushing’s given suspicious clinical features. Past history included hyper...

Introduction: Adrenocortical carcinoma (ACC) is rare, with an incidence of 0.5-2 cases per million. Although generally aggressive, prognosis is highly variable and difficult to predict. Unlike other malignancies, there are no biomarkers routinely available for use in patients with ACC to help guide management. Circulating cell free tumour derived DNA (ctDNA), the proportion of circulating cell free DNA (cfDNA) originating from tumour cells, is a liquid biopsy that is quickly g...

Background: Considering the high prevalence of metabolic and mental health issues associated with PCOS, it is important to screen for these routinely in clinic. We aimed to implement a standard approach to ensure we do this in our specialist PCOS clinic.Methods: We introduced a standard ‘PCOS clinic pack’ which included the following documents and data collected for analysis1. Checklist for doctors to e...

Introduction: Opportunistic infections are a recognised complication of severe hypercortisolism. We report a case of Pneumocystis Pneumonia (PCP for formerly named Pneumocystis carinii pneumonia) in patient with ectopic Cushing's syndrome (CS) caused by a metastatic neuroendocrine carcinoma of the lung.Case history: A 61-year old male attended the Acute Medical Unit for investigation and treatment of seve...

Background: Considering the high prevalence of metabolic and mental health issues associated with PCOS, it is important to screen for these routinely in clinic. We aimed to implement a standard approach to ensure we do this in our specialist PCOS clinic.Methods: We introduced a standard ‘PCOS clinic pack’ which included the following documents and data collected for analysis1. Checklist for doctors to e...

Introduction: Opportunistic infections are a recognised complication of severe hypercortisolism. We report a case of Pneumocystis Pneumonia (PCP for formerly named Pneumocystis carinii pneumonia) in patient with ectopic Cushing's syndrome (CS) caused by a metastatic neuroendocrine carcinoma of the lung.Case history: A 61-year old male attended the Acute Medical Unit for investigation and treatment of seve...

Introduction: Children and young people with T1DM living in the least deprived areas have better diabetes control vs those in most deprived areas with UK NPDA data suggesting that deprivation and ethnicity are associated with less use of technology.1Aims: 1. Review distribution of technology between different socio-economic and ethnic groups 2. To compare mean recent HbA1c results between groups using different combinations of technology<p...

Introduction: Hypoglycaemia following bariatric surgery is a recognised complication, secondary to increased incretin secretion to nutrient intake due to altered gut anatomy. It is predominantly postprandial, and usually occurs >6 months postoperatively. We report a case of insulinoma unmasked during the early postoperative period after sleeve gastrectomy (SG).Case presentation: A 49-year old female with severe obesity without diabetes underwent SG. ...

Introduction: The optimal management approach for incidental non-functioning pituitary microadenomas (micro-NFAs) is unclear. We aimed to capture current UK practice and identify changes following a 13-year interval.Methods: Two surveys on micro-NFAs were conducted in 2009 and 2022 (advertised by Society for Endocrinology). Hormonal/imaging evaluations were explored.Results: 2022: 150 clinicians participated. At baseline, ≥14...